I imagine in terms of medical care access and affordability or welfare stimulus, practically negligible, but in terms of CDC funding, science literacy, public policy, and general preparedness, it would be a whole lot better put together.
So I'd say... 10% fewer deaths? 200K vs. 220K deaths sounds about right.
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How would they have reacted worse than they did under Trump? It's easy to say "it can always get worse," but even 6-8 months into this thing you'll still find conservatives saying it's no big deal, you'll still find conservatives holding superspreader political events, and you'll still find conservatives proudly baking mask opposition into their day-to-day business (been to a gun store recently?). I'd say "at least they've stopped having armed marches on statehouses," but that seems a little silly considering the (at least semi-serious) plans to kidnap a governor over her covid response.