Off the top of my head, SpongeBob SquarePants, Danny Phantom, Fairly Oddparents, The Big Bang Theory and It's Always Sunny in Philadelphia all have jokes, if not the main plot point of the episode, that are just mocking the existence of LGBTQ people.
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They were good in the way that none of the characters seemed to care that much about the genders of people's partners. I also like how Randy and Lahey were totally unlike stereotypical gay clichés.
But I can see why the depiction of trans people was really not that great. Today you wouldn't make dumb jokes about straight men being "tricked" to have sex with trans women.
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