if you call everyone dude and a transfem person gets mad about it, don't get defensive. just say like "sorry, i won't do it again" and don't argue "actually it's gender neutral" or "i call everyone dude". even if you do, i guarantee she's heard that argument from someone who very much does not call people they see as women dude. i certainly have
same goes double for the word guy.
Interestingly here in the UK referring to a group as "ladies" regardless of men or women being in the group is actually pretty common.
Like "alroight ladiesss how's everyone doin then?" isn't an uncommon phrase you'd here someone say meeting up with a group in the pub.
it's done here in the states too, usually by a male speaker, when the context is extremely unserious and the audience is presumed to be majority or entirely men.