So if you make up the difference tomorrow, what will likely happen is that the curve of E entering your bloodstream won't have the sharp spike of the full dose all at once but will instead have 2 shallower curves that merge together and peter out at roughly the same rate it would have if you took it all at once. Since they sit between your muscle and fat layers, there's a bit of a buffer where it takes time for them to be absorbed into your bloodstream. It's not something I'd be too worried about. Sometimes I've made similar mistakes and felt better when I put myself back on track later in the day.

Going over your dose is more difficult as your only option really is to just wait it out.

But still, if you wanna reschedule your appointment I'd definitely do that. You'll be less stressed out overall.