so i just started hrt and im doing diy E monotherapy injections. im abt to do my 5th weekly injection. im planning on lowering my dosage bc i think i started too high. i was aiming to suppress my T fast but i think it happened already bc my cum is clear and watery and i ejaculate a small volume. my first week i was planning on doing estradiol enantate 11 mg every 14 days, but i didn’t like the huge difference between peak and trough that it would cause so i have been doing 5 mg weekly but that should put me around 300 pg/mL which i dont think is uncommon for monotherapy but it’s working so well i think a lower dose would be better.
i was considering doing 2 mg weekly enantate injections plus 2 mg daily oral E bc ur liver turns some estradiol into estrone and there’s some evidence that E1 helps feminize. is this a reasonable regimen? would planned parenthood prescribe me oral E as well as a testosterone cream/gel to prevent penis atrophy and help with performance ive been struggling since starting hrt? planned parenthood is prob my best option in my area. would they prescribe me 6 months of E if i act like im doing two 2 mg daily instead of one? like they prescribe for 90 days but it will last me 180
Seem good. Injections are the best method and injection monotherapy is often sufficient without needing a separate T blocker.
I'd agree with that.
Have you been able to do any blood tests?
If you are experiencing penis atrophy and want to avoid it and you haven't been able to do any blood tests, I think the cream/gel would be a great place to start and see how that goes, assuming it's possible to access in the USA. You could also try that in combination with a reduced E2 dose and see where that gets you.
I went down the rabbit hole of E1 a couple of years ago and didn't find any evidence at all. What did you find? If I were you, I'd just stick (ha ha ha) to the injections.
thanks for the help! this makes me feel a lot better! all the E1 articles i read say there’s no evidence. but i saw some trans ppl say it helped them feminize better. but that’s anecdotal so idk. also i was gonna get a blood test in 2 months, 3 months after starting hrt
anecdotal evidence is worth considering when it's something as poorly studied as trans health, but in this case I'd say since E2 injections are generally healthiest and you're already seeing changes, I wouldn't suggest changing to E1 unless you're seeing poor results after 1.5-2 years or so.