A long time ago I made a Crispr-Cas9 viral vector to knockout the DMRT1 gene in humans and had it manufactured. Just wondering what the responses to this would be seems as I haven't dared tell anyone until recently due to legalities around all this. For those who don't know what this gene is responsible for, wikipedia explains it well: https://e...

„Aren't you supposed to be on break?”

Yeah yeah, shut up :LIB:. This is really fucking cool and I want to share. OK????? :bird-mad:

In short, this fucking lady modified her balls to produce estrogen and apparently it worked. HOW THE FUCK????? :turtle-pogger:

Fucking imagine, a goddamn feminization vaccine :cat-trans:

God I'd love for something like this to finally exists so my comrades can live happier lives like holy fuck, this will be a state sponsored project during socialism I guarantee you that :bloomer:

  • kristina [she/her]M
    ·
    3 months ago

    virally transing america

    also how do i get some of this shit, how the fuck does she not go into detail? feels fake purely on that

      • kristina [she/her]M
        ·
        3 months ago

        https://archive.ph/MnUFI yeah like from what i can tell this is a multi million dollar process that hasnt been tested for this issue.

        • Blockocheese [any]
          ·
          3 months ago

          CRISPR CAS9 in previous human experiments failed because the human immune system doesn't like bacterial DNA

          This reminds me of the overly optimistic bathtub insulin posts

        • Chronicon [they/them]
          ·
          3 months ago

          https://www.youtube.com/watch?v=J3FcbFqSoQY it can be done by non-institutions on a budget, but that doesn't necessarily mean this is real.

    • iridaniotter [she/her]
      ·
      3 months ago

      virally transing america

      There's a novella about this but I forget its name

  • Awoo [she/her]
    ·
    3 months ago

    Not a lot of response from the OP there. Did they just disappear?

    Very interesting but would need some incredibly brave people to test. The biohack crowd just fucking with shit honestly amazes me.

  • QuillcrestFalconer [he/him]
    ·
    3 months ago

    1 step closer to the Culture baby. Pretty cool. Unfortunately, crispr-cas9 gene editing in humans can easily result in off target edits, so it might not be very safe

  • RNAi [he/him]
    ·
    3 months ago

    I would stick to hormone therapy

  • GirlPilot [she/her]
    ·
    3 months ago

    I'm pretty sure there are laws against gene editing your own gonads (Fears of tweaking your Germline genome to make superhumans)

    But overall pretty cool, an arguably even more dangerous way to castrate yourself :P I thought burdizzo clamps were scary.