Off the top of my head, SpongeBob SquarePants, Danny Phantom, Fairly Oddparents, The Big Bang Theory and It's Always Sunny in Philadelphia all have jokes, if not the main plot point of the episode, that are just mocking the existence of LGBTQ people.
Friends is so fucking bad with this if you've rewatched it even remotely recently. Ross's ex wife and Chandler's parents are handled terribly and they're constantly brought up.
or the number of times they make fun of chandler for being "gay" because he's... a toxic loser? and that makes him gay somehow?