dualmindblade [he/him]

  • 35 Posts
  • 391 Comments
Joined 4 years ago
cake
Cake day: September 21st, 2020

help-circle

  • Interesting read! So they have never significantly tapped into your chemistry or science knowledge? I have a college kid who doesn't love taking money from me and randomly lost a bunch of financial aid this year. Thinking of forwarding this info to them but I'm a little worried it would be demoralizing as a first non-work-study job..







  • Omg, that experience with your psychiatrist beating you for self medicating with moclobomide is like my worst nightmare. I have a very strict policy of lying to my doctors about that sort of thing and also recent recreational drug use (except cannabis) and I'm sure it has saved me some pain, but that said it seems like you got tremendously unlucky there, I can't imagine too many of my doctors reacting that way. It's hilarious though, you can confess to all kinds of "self medication" and they won't bat an eye, but if it's actual medicine it becomes super concerning!

    I am a burgerreich citizen unfortunately, also tried moclobomide a while back since it was easy to get on the gray market. It's really remarkable how different it is from the two I've recently been on. It was definitely activating for me despite, IIRC, it being slightly selective for mao-a. There must be some really complex pharmacology going on here, usually I find most drugs in the same class to have at least something in common in terms of how they make me feel but so far I'm not seeing any similarities whatsoever. The thing about inhibiting GABA does make me a bit concerned about trying phenelzine but maybe I'll get lucky, or who knows maybe this horrendous side effect will go away with the one I'm on. I really need to do more research here, I never went that deep since I never expected to be allowed to try these things. Gillman is a name I've heard in passing on the forums, sounds like that's a good place to start.

    I didn't know till relatively recently that selegiline was also easy to get online, since my main "pharmacy" doesn't carry it, but that is also going to be part of my backup plan, I assume I can crush it up and take it sublingually if it fails to be effective orally.

    Thanks for the detailed response, depression is a fuck and I also hope you end up winning the battle/war on the coming years!




  • Cycling through various psych meds is so unbelievably frustrating. Turns out my current psych doc is willing to prescribe MAOIs which is great because I've always wanted to look into that class. Started with selegiline patch, it actually seemed like it might be helpful, I at least had more energy and motivation, but turns out I'm allergic to the adhesive and I kept reacting to it more and more until it was basically one big hive underneath when I took it off. Doctor is unwilling to prescribe oral or sublingual form, saying there's not enough evidence for its effectiveness on depression..

    Now I'm on removedlcypromine (parnate), which is actually what I would have picked for myself to start off with. After 2 months ramping up it couldn't be more different than the last med, I'm sleepy all the time, 0 motivation. I haven't gotten a single thing done for like 3 weeks and have called in to work 3 times. I'm not sure whether to try and power through or taper off but either way I'm in for quite a bit more of this since, unlike selegiline, you cannot quit this one cold turkey. Next up would be phenelzine (nardil), which is also very likely to make me sleepy.

    I want to give these a fair shot, after the MAOIs there's basically nothing left to try, over 20 years I've thoroughly explored every other class of depression med, but I also have to weigh that against my functionality, I can't just take a year off of work to dick around with drugs that each only have a sliver of a chance of being effective. I guess I should feel lucky, there are a lot of jobs I would already have been fired from for tardiness and absenteeism, and getting a doctor who's willing to prescribe supposedly dangerous stuff instead of just yet another ssri, SNRI, tricyclic, is difficult and expensive.









  • @AmericaDelendaEst@hexbear.net

    https://hexbear.net/comment/5528955

    Okay, the one nostril thing is actually normal! Most people breath primarily or entirely through one nostril at a time, with the dominant nostril switching every few hours. When I go off nasal spray (gradually) this is what happens to me and it drives me nuts. Like, if I'm entirely healthy and no allergens I can sort of breath through both, maybe 80/20, and it's only a little bothersome but the moment I get any congestion at all at least one is plugged up and I just cannot handle it. Probably I "cured" myself of the nasal cycle at a very young age and got used to it.

    If you do the same yes you will definitely get physically dependent but for me at least I have never had to increase the frequency or amount I'm using over time (literally like 35 years of continuous use). Actually like mentioned I've gone from full strength oxymetazoline to about 1/4, it works for 6 hours or so. Phenylephrine spray is much weaker but still causes dependence.

    As far as I can tell the only negative of being addicted is you will freak the fuck out and be miserable for a few days if you should find yourself without it. I am a habitual nicotine user and if I had to choose between nasal spray and my vape it would be no choice at all, nasal spray plz