As a reminder, be sure to properly give content warnings and put sensitive subjects behind proper spoiler tags. It's for the mental health of not just your comrades, but yourself as well.
Here is a screenshot of where to find the spoiler button.
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My healthcare conglomerate uses an informed consent model. It wasn't really your question, but there was no diagnosis. Just, this is what it does. These are the risks. Do you still want it? Great, see you in three months for a hormone check.
Psychologically estrogen has down stream effects on oxytocin (the bonding hormone) and serotonin (the rest and digest hormone).
I think other posters covered physical stuff well.