German man got 217 COVID shots over 29 months—here’s how it went
It conflicts with concerns of repeat boosters, but authors warn against hypervaccination.
A 62-year-old man in Germany decided to get 217 COVID-19 vaccinations over the course of 29 months —for "private reasons." But, somewhat surprisingly, he doesn't seem to have suffered any ill effects from the excessive immunization, particularly weaker immune responses, according to a newly published case study in The Lancet Infectious Diseases.
The case is just one person, of course, so the findings can't be extrapolated to the general population. But, they conflict with a widely held concern among researchers that such overexposure to vaccination could lead to weaker immune responses. Some experts have raised this concern in discussions over how frequently people should get COVID-19 booster doses.
In cases of chronic exposure to a disease-causing germ, "there is an indication that certain types of immune cells, known as T-cells, then become fatigued, leading to them releasing fewer pro-inflammatory messenger substances," according to co-lead study author Kilian Schober from the Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene. This, along with other effects, can lead to "immune tolerance" that leads to weaker responses that are less effective at fighting off a pathogen, Schober explained in a news release.
My guess is that his t-cells are fine because he's had constant antibodies so the t-cells haven't had to mop up anything, and also it's not a live virus. If you are living life like it's pre-covid times, you're most certainly being constantly exposed to covid anyway.
If you aren't over 65, or immunocompromised, and you find a way to get two vaccines a year, you'll probably be fine. People doing this have had mixed results in regards to how the 1-per year recommendation is being enforced and the CDC official covid advice is now "fuck it, do whatever, yolo", so why not?
If you got an MRNA in the fall, maybe try novavax for less side effects and a slightly different spectrum of protection.
https://time.com/6852933/covid-19-217-vaccines/
It's not clear why the man wanted so many vaccinations or how he obtained them. But after reading news reports of the man's story, scientists at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) became intrigued and wanted to study how the vaccinations affected his immune system. The man—who told researchers he hadn't experienced side effects from his shots—volunteered to provide blood and saliva samples to the scientists and allowed them to mine his health records so that they could better understand what effect aggressively stimulating the immune system with a COVID-19 vaccine might have. Even during this analysis, the man requested and received an additional two COVID-19 shots, against the advice of the study researchers. [emphasis mine]
volunteered to provide blood and saliva samples
Don't do it! It's a vampire pyramid scheme!
how else are the vampires gonna get vaxxed? ill volunteer extra blood, just to make sure we dont get some kind of cursed supercovid from em
I found a YouTube link in your comment. Here are links to the same video on alternative frontends that protect your privacy:
He was tested for antibodies and had no sign of covid infection.I didn't say he had a covid infection or antibodies, I said he was made of covid.
Agreed, at that point that's a gestalt covid organism trying to increase in biomass
Yeah, okay, but is he sterile?
My nearly 80 year old father was concerned about the vaccine due to fears of becoming sterile.
His antibodies' ability to neutralize SARS-CoV-2 appeared to be between fivefold and 11-fold higher than in controls, but the researchers noted that this was due to a higher quantity of antibodies, not more potent antibodies.
Fucking Zerg rushing COVID broke the meta
I still remember when that guy said that COVID was more dangerous than HIV/AIDS, he was a bit mad
To incentivise people to get vaxxed, some municipalities started giving out perks like a free Bratwurst to accompany the vaccination. Needless to say that some Germans ended up abusing this system for a free glizzy.
So two vaccinations a year is ideal. The annual rhetoric is inaccurate? Company was going around last week offering boosters and I declined because I was boosted back then.
The official line is that they are not needed except for high risk groups because b and t-cell immunity should be sufficient after antibodies wane. Generally, for most people, antibodies peak after about three to four months, and are mostly gone after 6 months. If your antibodies are gone and you get infected, you will be relying on b and t-cells and rolling the dice on how quickly they react to the virus once it's in the bloodstream. After a year you aren't really protected much at all, because covid is rapidly mutating, but the immune system is complex and people react differently, so there are a bunch of factors which effect everything, like if you were exposed to covid throughout the year, and how much of it you were exposed to, and when, and which mutations, and how different those mutations are from what your immune system is prepared for, and how your immune system responded to all of that.
But, yes, if you want covid antibodies year round, you'd want a booster or new vax every six months.
considering how captured the centers for disease circulation is, i'm guessing the real numbers are twice a year for most people and 3-4 if you're at-risk
...why?
or more importantly, how? they're so hard to get. at least they are here
Some people are going to CVS and getting them as long as they say they haven't had a vaccine within 4 months. No one's really keeping track anymore, except maybe your health insurance who may or may not deny payment.
that's pretty cool. I think they're still keeping track here, which sucks, they're very strict about it
